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Testosterone replacement therapy improves health-related quality of life for patients with late-onset hypogonadism: a meta-analysis of randomized controlled trials


, : Testosterone replacement therapy improves health-related quality of life for patients with late-onset hypogonadism: a meta-analysis of randomized controlled trials. Andrologia (): -

NlmCategory="UNASSIGNED">Although testosterone replacement therapy can restore serum testosterone concentrations to normal level in late-onset hypogonadism patients, whether it can improve patients' quality of life remains uncertain. Therefore, we perform a meta-analysis of randomized controlled trials on this issue. Five randomized controlled trials total 1,212 patients were included. Fixed-effect model was used to calculate the weighted mean difference of score of Aging Males' Symptom rating scale. Our result reveals that testosterone replacement therapy improves patients' health-related quality of life in terms of the decrease in the AMS total score [WMD = -2.96 (-4.21, -1.71), p < .00001] and the psychological [WMD = -0.89 (-1.41, -0.37), p = .0008], somatic [WMD = -0.89 (-1.41, -0.37), p = .0008] and sexual [WMD = -1.29 (-1.75, -0.83), p < .00001] subscale score.

US$19.90

PMID: 27389320

DOI: 10.1111/and.12630


Other references

Kondo, N.; Endo, S., 1987: Studies on a visual sensor for recognizing fruit. I. Discrimination experiment using 3 colour filters. A vision system using a small television camera lens, an area image sensor and green, blue and red filters was tested for distinguishing tomatoes, sweet peppers, aubergines, mandarin oranges, persimmons and cucumbers from their leaves. Output from...

Klingstedt C.; Baehrendtz S.; Bindslev L.; Hedenstierna G., 1985: Lung and chest wall mechanics during differential ventilation with selective positive end expiratory pressure. Eight patients free from cardio-pulmonary disease and with a mean age of 46 years were studied during general anaesthesia in the lateral position. Measurements of hemithoracic mechanics were made during four different modes of ventilation: 1. Cove...

Mullaney, P.B.; Karcioglu, Z.A.; al-Mesfer, S.; Abboud, E.B., 1997: Presentation of retinoblastoma as phthisis bulbi. Purpose. We sought to determine the incidence of retinoblastoma patients who presented with phthisis bulbi. Methods. The medical records of 272 patients in the King Khaled Eye Specialist Hospital Retinoblastoma Registry were retrospectively studie...

Vasilenko, V.A.; Reĭzenbuk, V.G.; Reĭnaru, I.K.; Sarv, I.R.; Iyks, S.R., 1985: Detection of Epstein-Barr viral antibodies in patients with acute viral hepatitis. Serum samples obtained from 44 patients with virus A hepatitis, 23 patients with virus B hepatitis, 65 patients with virus non A, non B hepatitis and 100 healthy adults were studied for the presence of Epstein-Barr (EB) virus in the indirect immun...

Silva, R.Y.H.; Lailhacar, S., 2000: Transpiration efficacy standard of gaseous exchange of species of the genus Atriplex from the arid mediterranean zone of Chile. The transpiration efficacy, defined as the relationship between the quantity of carbon dioxide fixed per unit of water transpired, was determined for 8 provenances belonging to Atriplex halimus, A. nummularia, A. atacamensis, A. canescens and A. u...

Summers, D.J.; Robblee, A.R., 1985: Comparison of apparent amino acid digestibilities in anesthetized versus sacrificed chickens using diets containing soybean meal and canola meal. To estimate apparent amino acid digestibility (AAAD), samples of digesta were taken from segments of the terminal third of the ileum and the large intestine of male broiler chicks given diets containing varying amounts of soyabean oilmeal or canol...

Mitchell, J.C.; Schmid, J.M., 1973: Spruce beetle: mortality from solar heat in cull logs of Engelmann spruce. In field tests in Wyoming in 1970-71, exposure of cull logs of Engelmann spruce (Picea engelmanni) infested by Dendroctonus rufipennis (Kby.) to solar heat in a cleared area resulted in at least 90% mortality of the Scolytid on the top surface of...

Mcclelland, Gah, 1975: Man-made mosquito problems. Insect world digest: 2 (3) 19-23

Blouin, M.S.; Bonner, K.M.; Cooper, B.; Amarasinghe, V.; O'Donnell, R.P.; Bayne, C.J., 2013: Three genes involved in the oxidative burst are closely linked in the genome of the snail, Biomphalaria glabrata. Allelic variation at the Cu-Zn superoxide dismutase (SOD1) locus has been shown to be associated with resistance of the snail, Biomphalaria glabrata, to infection by the trematode parasite, Schistosoma mansoni. SOD1 catalyses the production of hyd...

Hamlyn P.R.; Bonatti E., 1980: On the nature of the oceanic upper mantle. Eos, Transactions, American Geophysical Union: 7, Pages 374. 1980.