geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Th17 expression and IL-17 levels in laryngeal squamous cell carcinoma patients


, : Th17 expression and IL-17 levels in laryngeal squamous cell carcinoma patients. Acta Oto-Laryngologica 136(5): 484-490

The Th17 cell frequency in peripheral blood and levels of IL-17 showed significant differences between patients with laryngeal squamous cell carcinoma and those with vocal cords polyps. Serum levels of IL-17 were correlated with laryngocarcinoma staging. To investigate associations among the frequency of Th17 cells, levels of IL-17, and laryngeal squamous cell carcinoma. Eighty in-patients with laryngeal squamous cell carcinoma and 114 in-patients with polypus of the vocal cord were enrolled. Th17 cell frequencies in peripheral blood and serum levels of IL-17 were measured by flow cytometry and enzyme-linked immunosorbent assay, respectively. The tissue expression levels of IL-17 mRNA transcripts and protein were measured using quantitative RT-PCR or immunohistochemical detection, respectively. Th17 cell frequencies in peripheral blood and serum concentrations of IL-17 were significantly higher in patients with laryngocarcinoma compared with those in patients with polyps (p < 0.01 for both Th17 cells and IL-17 levels). Serum concentrations of IL-17 were significantly higher in patients with advanced laryngocarcinoma than in patients with early laryngocarcinoma (p < 0.01). The mRNA and protein levels of IL-17 were significantly higher in laryngocarcinoma tissues than in adjacent normal tissues (p < 0.01 for mRNA levels, p < 0.05 for protein levels).

US$19.90

PMID: 27052965

DOI: 10.3109/00016489.2015.1126857


Other references

Golin, C.E.; Haley, D.F.; Wang, J.; Hughes, J.P.; Kuo, I.; Justman, J.; Adimora, A.A.; Soto-Torres, L.; O'Leary, A.; Hodder, S., 2016: Post-traumatic Stress Disorder Symptoms and Mental Health over Time among Low-Income Women at Increased Risk of HIV in the U.S. Women living in poverty suffer more post-traumatic stress disorder (PTSD) symptoms than do members of the general population; however we know little about factors associated with changes in their PTSD symptoms over time. Using data from HPTN 064,...

Kato, I.; Yokokura, T.; Mutai, M., 1985: Induction of tumoricidal peritoneal exudate cells by administration of Lactobacillus casei. The lifespan of mice into which Meth A fibrosarcoma was transplanted intraperitoneally (i.p.) was prolonged by i.p. treatment with Lactobacillus casei YIT 9018 (LC 9018). Treatment with LC9018 before the tumor inoculation (pre-treatment), was more...

Du, G.; Hathout, R.M.; Nasr, M.; Nejadnik, M.Reza.; Tu, J.; Koning, R.I.; Koster, A.J.; Slütter, B.; Kros, A.; Jiskoot, W.; Bouwstra, J.A.; Mönkäre, J., 2017: Intradermal vaccination with hollow microneedles: A comparative study of various protein antigen and adjuvant encapsulated nanoparticles. In this study, we investigated the potential of intradermal delivery of nanoparticulate vaccines to modulate the immune response of protein antigen using hollow microneedles. Four types of nanoparticles covering a broad range of physiochemical par...

Fular, W.; Bilharz, T., 1951: Im memoria Theodor Bilharz. Die Medizinische Welt 20(50): 1599-1599

Chandler Philip B., 1969: Transform-transpeninsular features in Baja California from orbital photographs. Eos, Transactions, American Geophysical Union: 1, Pages 672. 1969.

Moghadamnia, A.A.; Partovi, M.; Mohammadianfar, I.; Madani, Z.; Zabihi, E.; Hamidi, M.R.; Baradaran, M., 2009: Evaluation of the effect of locally administered amitriptyline gel as adjunct to local anesthetics in irreversible pulpitis pain. Amitriptyline is one of the most common tricyclic antidepressants, which binds to pain sensory nerve fibers close to the sodium channel; hence, it could interact to some degree with receptors of local anesthetics. This study was designed to assess...

Matyka, S.; Sagan, A.; Jaskiewicz, T., 1996: Stability of vitamins A and E in feed premixes containing isolated fractions of trace elements. Vitamins A and E were more stable during storage in a premix containing Bioplex (minerals and starch) than in normal premixes. Isolation of the mineral fraction increased the stability of the 2 vitamins, especially that of vitamin A. In a normal p...

Boulay, F.; Chevallier, T.; Staccini, P.; Chichmanian, R.M., 1997: Public health education integrated in hospital. An internship proposal, "Medical information and pharmacology". According to a recent circular reforming french medical studies, we propose a teaching of medical information and pharmacology in situ within hospital instructions. Students could acquire an investigation methodology on the medicine economy. It wi...

Fiorani, R., 1968: Considerations on the need for production of an anatomically correct seat. Minerva Medica 59(77): 4062-4064

Raoch, V.; Rodríguez-Pascual, F.; López-Martínez, V.; Medrano-Andrés, D.; Rodríguez-Puyol, M.; Lamas, S.; Rodríguez-Puyol, D.; López-Ongil, S., 2012: Nitric oxide decreases the expression of endothelin-converting enzyme-1 through mRNA destabilization. Endothelial function depends on the equilibrium in the synthesis of vasoactive endothelial factors. It is well known that endothelin and nitric oxide (NO) exhibit reciprocal regulation. We assessed the ability of NO to regulate endothelin-converti...