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Time-resolved optically stimulated luminescence of Al2O3:C for ion beam therapy dosimetry


, : Time-resolved optically stimulated luminescence of Al2O3:C for ion beam therapy dosimetry. Physics in Medicine and Biology 60(17): 6613-6638

The objective of this study was to characterize the time-resolved (TR) optically stimulated luminescence (OSL) from Al2O3:C detectors and investigate methodologies to improve the accuracy of these detectors in ion beam therapy dosimetry, addressing the reduction in relative response to high linear energy transfer (LET) particles common to solid-state detectors. Al2O3:C OSL detectors (OSLDs) were exposed to proton, (4)He, (12)C and (16)O beams in 22 particle/energy combinations and read using a custom-built TR-OSL reader. The OSL response rOSL, relative to (60)Co gamma dose to water, and the ratio between the UV and blue OSL emission bands of Al2O3:C (UV/blue ratio) were determined as a function of the LET. Monte-Carlo simulations with the multi-purpose interaction and transport code FLUKA were used to estimate the absorbed doses and particle energy spectra in the different irradiation conditions. The OSL responses rOSL varied from 0.980 (0.73 keV μm(-1)) to 0.288 (120.8 keV μm(-1)). The OSL UV/blue ratio varied by a factor of two in the investigated LET range, but the variation for (12)C beams was only 11%. OSLDs were also irradiated at different depths of carbon ion spread-out Bragg peaks (SOBPs), where it was shown that doses could be obtained with an accuracy of ± 2.0% at the entrance channel and within the SOBP using correction factors calculated based on the OSL responses obtained in this study. The UV/blue ratio did not allow accurate estimation of the dose-averaged LET for (12)C SOBPs, although the values obtained can be explained with the data obtained in this study and the additional information provided by the Monte-Carlo simulations. The results demonstrate that accurate OSLD dosimetry can be performed in ion beam therapy using appropriate corrections for the OSL response.

US$19.90

PMID: 26270884

DOI: 10.1088/0031-9155/60/17/6613


Other references

Sager, R.R.manis, Z., 1971: Methods of genetic analysis of chloroplast DNA in Chlamydomonas. Symp auton biog mitochondria chloroplasts Canberra: ub 1971) 250-259

Ling, G.S.F.; Rhee, P.; Ecklund, J.M., 2010: Surgical innovations arising from the Iraq and Afghanistan wars. The delivery of combat casualty care poses numerous challenges including austere conditions, limited supplies and medical personnel, and multiple simultaneous patients. However, the exigent circumstances of the battlefield compel the development o...

Schieber, E.; Rodriguez, V.A.E.; Fuentes F.S., 1964: Distribution of Puccinia sorghi and P. polysora in Central Mexico. The data presented show a clear relationship between the 2 spp. on maize and specific elevations, P. sorghi being found at high elevations and P. polysora at lower, where higher temps, prevail. P. polysora has, however, been found at 4, 000 ft. in...

du Toit, P.L.; van Kradenburg, J.; Niehaus, D.; Stein, D.J., 2001: Comparison of obsessive-compulsive disorder patients with and without comorbid putative obsessive-compulsive spectrum disorders using a structured clinical interview. Increasing attention has been paid to the possibility that a range of disorders, the putative obsessive-compulsive spectrum disorders (OCSDs), may share overlapping phenomenological and neurobiological features with obsessive-compulsive disorder (...

' Akau ' ola, L.; ' Ilaiu, L. ' ; Samate, ' A.; Burke, K. ' ; Moimoi, T., 1980: Tonga. In the first article, The social and cultural impact of tourism in Tonga, the three authors acknowledge the financial benefits and the jobs created by tourism, but turn their attention to some less desirable side effects such as accelerated social...

Silvestri, L.; Sonzogni, L.; D.S.lvestri, A.; Gritti, C.; Foti, L.; Zavaglia, C.; Leveri, M.; Cividini, A.; Mondelli, M.U.; Civardi, E.; Silini, E.M., 2003: CYP enzyme polymorphisms and susceptibility to HCV-related chronic liver disease and liver cancer. Cancer risk can be influenced by the exposure to endogenous or environmental toxins. Polymorphic enzymes involved in the metabolic activation/detoxification of carcinogens may account for individual variations of risk. We studied the polymorphisms...

Harwalkar, V.; Cholette, H.M.kellar, R.; Emmons, D., 1993: Relation between proteolysis and astringent off-flavor in milk. Pasteurized skim milk was treated with 10 proteinases from psychrotrophic bacteria and with plasmin, the naturally occurring milk proteinase, and evaluated organoleptically for astringency. At comparable levels of digestion (extent of proteolysis...

Chardot, C.; Parache, R., 1967: Pure myxomas of the conjunctival membranes of the extremities and the abdominal wall. Apropos of 19 cases. Bulletin du Cancer 54(3): 297-318

Vertruyen, M.; Bosschaerts, T.; Barroy, J.P., 1994: Inflammatory aneurysms of the abdominal aorta. Review of 7 cases. Seven cases of inflammatory aneurysm of the abdominal aorta were reviewed. The authors discuss the different diagnostic modalities (ESR, CT-scan, IVU) and some peroperative technical details in the surgical approach to this pathology in order to l...

Lock Andersen J.; Hastrup N.C.; Drzewiecki K., 1989: The metastasizing of cutaneous melanoma. Scandinavian Journal of Plastic & Reconstructive Surgery & Hand Surgery 23(2): 153-156