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Twelve-Month Results of a Single or Multiple Dexamethasone Intravitreal Implant for Macular Edema following Uncomplicated Phacoemulsification

, : Twelve-Month Results of a Single or Multiple Dexamethasone Intravitreal Implant for Macular Edema following Uncomplicated Phacoemulsification. Biomed Research International 2015: 362564-362564

The clinical efficacy of one or two intravitreal injections of a continued deliverance dexamethasone 700 μg implant in ten patients with persistent macular edema following uncomplicated phacoemulsification was evaluated. Complete ophthalmological examination and spectral domain optical coherence tomography were carried out. Follow-up was at day 7 and months 1, 2, 4, 6, 8, and 12. At baseline mean best corrected visual acuity was 62 Early Treatment Diabetic Retinopathy Study Chart letters, which showed statistically significant improvement at each follow-up, except at month 6, to reach 79 letters at month 12 (P = 0.018). Prior to treatment mean central foveal thickness was 622 μm, which showed statistically significant improvement at each follow-up to reach a mean value of 282 μm (P = 0.012) at month 12. Five patients received a second dexamethasone implant at month 7. Two patients were excluded from the study at months 4 and 8. Intraocular pressure remained stable during the study period with the exception of mild increase in two patients requiring topical therapy. In conclusion there was statistically significant improvement of best corrected visual acuity and mean central foveal thickness with one or two intravitreal dexamethasone implants over 12 months.


PMID: 26509151

DOI: 10.1155/2015/362564

Other references

Lung, F-Wey.; Chiang, T-Liang.; Lin, S-Jean.; Lee, M-Chih.; Shu, B-Ching., 2010: Child developmental screening instrument from six to thirty-six months in Taiwan birth cohort study. A reliable and valid assessing tool to detect the problem before the child becomes deviant is very important. This study aimed to further test the reliability and validity of developmental screening instrument for follow-up of thirty-six months ch...

Winkler B.; Richart R.M., 1989: Human papillomavirus infections introduction. Winkler, B And R M Richart (Ed ) Clinical Practice Of Gynecology, Vol 1 No 2 Human Papillomavirus Infections Ix+259p Elsevier Science Publishing Co , Inc : New York, New York, Usa; Amsterdam, Netherlands Illus 1-3

Hillenbrand, H.J., 1956: Participation of the gastrointestinal tract in endangitis obliterans (Winiwarter-Buerger disease). Klinische Wochenschrift 34(23-24): 635-639

Garcia, H.H.; Gilman, R.H.; Gonzalez, A.E.; Verastegui, M.; Tsang, V.C.W.; The Cysticercosis Working Group, 2002: What have we learnt from epidemiological studies of Taenia solium cysticercosis in Peru?. Singh, Gagandeep [Editor, Reprint Author], Prabhakar, Sudesh [Editor] Taenia solium cysticercosis: From basic to clinical science : 75-81

Singer A.; Mueller G., 1983: Diagenesis in argillaceous sediments. Pages 115-212 1983

Daughton D.M.; Millatmal T.; Thompson A.B.; Boomsma J.; Rennard S.I., 1992: Nicotine yield of cigarettes is a determinant of smoking behavior among heavy cigarette users. American Review of Respiratory Disease 145(4 PART 2): A686

Serralheiro, J.A., 1983: Effect of gibberellic acid and bunch thinning on berry volume of cultivars capable of raisin production. In trials with the grapevine cultivars Major and Cibele, GA at 50, 100 or 200 p.p.m. was applied in mid-June or the bunches were thinned by one third of their size. GA, especially at 200 p.p.m., increased berry volume whereas thinning had little e...

Lamb, W.K.; Cameron, T.W.M., 1967: Biologists and biological research since 1864. Unknown

Lee, L.; Elliott, R.L., 2008: Cervical spondylotic myelopathy in a patient presenting with low back pain. Journal of Orthopaedic and Sports Physical Therapy 38(12): 798-798

Zhen, Y.S.; Li, D.D.; Lin, F.T.; Li, Q.; Tian, P.Y.; Xue, Y.C.; Yang, X.P., 1979: Study on the antitumor activities and the toxicities of zhengguangmycins A5 and A2. Yao Xue Xue Bao 14(2): 83-90