geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Use of Blood Products and Diseased Ascending Aorta Are Determinants of Stroke After Off-Pump Coronary Artery Bypass Grafting


, : Use of Blood Products and Diseased Ascending Aorta Are Determinants of Stroke After Off-Pump Coronary Artery Bypass Grafting. Journal of Cardiothoracic and Vascular Anesthesia 29(5): 1180-1186

To examine the effect of blood products on the occurrence of stroke after coronary artery surgery. Institutional retrospective analysis. University hospital. One thousand three hundred fourteen patients undergoing coronary artery surgery. Off-pump coronary artery bypass grafting (OPCAB). Epiaortic ultrasound was performed in all patients. Complete pre-, intra- and postoperative data including the number of transfused blood products as well as the timing, type, and course of stroke were available in all patients. Postoperative stroke occurred in 23 patients (1.8%). Logistic regression identified transfusion of platelets (3.6% v 1.1%, p = 0.003, OR 3.34, 95%CI 1.46-7.67) and diseased ascending aorta (3.0% v 1.2%, p = 0.022, OR 2.64, 95% CI 1.15-6.06) as independent predictors of stroke. When these variables were adjusted for CHA2DS2VASc (p = 0.005, OR 1.44, 95% CI 1.12-1.86), only transfusion of platelets (p = 0.012, OR 2.91, 95% CI 1.26-6.70) was associated with stroke. Neither nadir hematocrit on the day of surgery nor nadir hematocrit during the perioperative period was an independent predictor of stroke. Chi-squared automatic interaction detection analysis identified solvent/detergent-treated plasma (Octaplas; Octapharma AG, Lachen, Switzerland) units >2 and platelet units >4 along with diseased ascending aorta as independent predictors of stroke. The stroke rate was 8.9% in patients receiving >2 units of Octaplas and having a diseased ascending aorta. In patients receiving ≤2 units of Octaplas, the stroke rate was as high as 3.8% in patients receiving >4 units of platelets. The results of this study indicated that atherosclerosis of the ascending aorta as well as transfusion of platelets and/or Octaplas were independent predictors of stroke after OPCAB.

US$19.90

PMID: 26022913

DOI: 10.1053/j.jvca.2015.02.021


Other references

Schwab, N.V.; Eberlin, M.N., 2013: Mass spectrometry made easy: the quest for simplicity. Mass spectrometry (MS) is generally viewed as a highly complex and demanding technique, full of difficulties and apprehensions. Ease and simplicity have been infrequently used descriptors of MS but a series of revolutionary developments is turning...

Digel, C.; Riede, J.O.; Brose, U., 2011: Body sizes, cumulative and allometric degree distributions across natural food webs. The distributions of body masses and degrees (i.e. the number of trophic links) across species are key determinants of food-web structure and dynamics. In particular, allometric degree distributions combining both aspects in the relationship betwe...

Mathur, V.Prakash.; Dhillon, J.Kaur.; Logani, A.; Agarwal, R., 2014: Development and validation of oral health-related early childhood quality of life tool for North Indian preschool children. The purpose of this study was to develop a reliable instrument [Oral Health related Early Childhood Quality of Life (OH- ECQOL) scale] for measuring oral health related quality of life (OHrQoL) in preschool children in North Indian population. Fou...

Sofka, C.M.; Adler, R.S., 2003: Original report. Sonographic evaluation of shoulder arthroplasty. The objective of our study was to review our experience using sonography to evaluate the rotator cuff after arthroplasty. Diagnostic reliability, with respect to surgical findings, as well as subjective assessment of the examinations, including th...

Besken, M., 2016: Picture-perfect is not perfect for metamemory: Testing the perceptual fluency hypothesis with degraded images. The perceptual fluency hypothesis claims that items that are easy to perceive at encoding induce an illusion that they will be easier to remember, despite the finding that perception does not generally affect recall. The current set of studies tes...

Reed, C., 2008: Life in old lava. Scientific American 299(1): 28, 30-28, 30

Murray, H.W., 1981: Interaction of Leishmania with a macrophage cell line. Correlation between intracellular killing and the generation of oxygen intermediates. The promastigote form of Leishmania donovani and Leishmania tropica, the etiologic agents of visceral and cutaneous leishmaniasis, respectively, readily parasitize unstimulated J774G8 macrophage-like cells, whereas 80-95% of the same promastigotes...

Cheng, L.K.; Sands, G.B.; French, R.L.; Withy, S.J.; Wong, S.P.; Legget, M.E.; Smith, W.M.; Pullan, A.J., 2005: Rapid construction of a patient-specific torso model from 3D ultrasound for non-invasive imaging of cardiac electrophysiology. One of the main limitations in using inverse methods for non-invasively imaging cardiac electrical activity in a clinical setting is the difficulty in readily obtaining high-quality data sets to reconstruct accurately a patient-specific geometric...

Mcmillan, C., 1965: Ecotypic differentiation within four North American prairie grasses. 2. Behavioral variation within transplanted community fractions. Ecotypic differentiation in transplanted clones of Andropogon scoparius, A. gerardi, Panicum virgatum and Sorghastrum nutans showed N. to S. correlations. Southern clones had earliest spring activity, latest flowering and latest onset of winter-do...

Martín, Jé.Jesús.Martín.; González, M.del.Puerto.López.del.Amo., 2011: The sustainability of the Spanish National Health System. The Spanish National Health System (SNHS) has sustainability problems resulting from weaknesses in institutional design and governance compounded by the economic crisis it faces. The global economic crisis has had a particularly virulent impact in...