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Ventilatory Dysfunction in Parkinson's Disease

, : Ventilatory Dysfunction in Parkinson's Disease. Journal of Parkinson's Disease 6(3): 463-471

In contrast to some other neurodegenerative diseases, little is known about ventilatory dysfunction in Parkinson's disease (PD). To assess the spectrum of ventilation disorders in PD, we searched for and reviewed studies of dyspnea, lung volumes, respiratory muscle function, sleep breathing disorders and the response to hypoxemia in PD. Among the studies, we identified some limitations: (i) small study populations (mainly composed of patients with advanced PD), (ii) the absence of long-term follow-up and (iii) the absence of functional evaluations under "off-drug" conditions. Although there are many reports of abnormal spirometry data in PD (mainly related to impairment of the inspiratory muscles), little is known about hypoventilation in PD. We conclude that ventilatory dysfunction in PD has been poorly studied and little is known about its frequency and clinical relevance. Hence, there is a need to characterize the different phenotypes of ventilation disorders in PD, study their relationships with disease progression and assess their prognostic value.


PMID: 27314755

DOI: 10.3233/JPD-160804

Other references

Pai, H.H.; Ko, Y.C.; Chen, E.R., 1993: Killing effect of gamma irradiation on Angiostrongylus cantonensis in snails. Cobalt-60 gamma irradiation was used to kill the larvae of Angiostrongylus cantonensis in four groups of snails that were irradiated at a rate of 15.4 Gy/min for 16.23 min (0.25 kGy), 32.47 min (0.50 kGy), 48.70 min (0.75 kGy), and 64.94 min (1.00...

Achard, Ch, 1932: Legons cliniques sur les maladies du sang et des organea hematopoietiques. This monograph is in the form of a set of clinical lectures dealing with the following subjects: hemophilia, purpura, pernicious anemia, myelogenous and lymphatic leukemia, aleukemic leukemia, acute leukemia, hypogranulocytosis, malignant granulom...

Peyman, G.A.; Katoh, N.; Tawakol, M.; Khoobehi, B.; Federman, J., 1987: Contact Nd:YAG laser for use in oculoplastic surgery. We used a contact Nd:YAG laser with a sapphire tip to perform blepharoplasties in rabbits, and to cut bone in the orbital rim. All procedures were performed easily and without intraoperative hemorrhage.

Gregson, R.A.; Smith, D.A., 1981: The clinical assessment of olfaction: differential diagnoses including Kallman's syndrome. Journal of Psychosomatic Research 25(3): 165-174

Corradini, M.G.; Engel, R.; Peleg, M., 2001: Sensory thresholds of consistency of semiliquid foods: evaluation by squeezing flow viscometry. Identification of subtle textural differences or changes in foods in isolation has been a difficult task because they are usually accompanied by differences or changes in other sensory properties. Textural modification of semiliquid foods can be e...

Busel' B.I.; Moldavan M.G., 1987: Influence of food motivation on reaction of neurons in the cat somatic cortex during instrumental reflex. Spike activity of neurons (areas 3, 4) was studied in cats during conditioned placing reaction before and after food satiation. After feeding the background activity increased in 2/3 of recorded neurons, tonic component of neuronal reaction decrea...

Tanzarella C.; Modesti A.; D.S.lvia R.; Vitagliano E., 1979: Variation of the symmetrical asymmetrical ratio in chromatid interchanges during the various phases of the cell cycle of human lymphocytes in vitro. The aim was to verify whether in a human euploid cell system, such as lymphocyte cultures in vitro, there is a differential pattern of induction of chromatid exchanges in the various phases of the cycle. The results indicate that for human lymphoc...

Dominguez, P.Guadalupe.; Frankel, N.; Mazuch, J.; Balbo, I.; Iusem, N.; Fernie, A.R.; Carrari, F., 2013: ASR1 mediates glucose-hormone cross talk by affecting sugar trafficking in tobacco plants. <I>Asr</I> (for <I>ABA</I>, <I>stress</I>, <I>ripening</I>) genes are exclusively found in the genomes of higher plants, and the encoded proteins have been found localized both to the nucleus and cyt...

Marcos, P.J.; Sanjuán, P.; Huerta, A.; Nieto-Codesido, I.; Ferreira-Gonzalez, Lía.; Sibila, O.; Restrepo, M.I., 2017: Relationship Between Severity Classification of Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Clinical Outcomes in Hospitalized Patients. Limited data are available regarding the impact of the potential validation of the Canadian Thoracic Society (CTS) guidelines recommendations in classifying patients with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in...

Hubbard, T.R.; Rydin, R.A.; Burns, T.D., 1997: A coupled deterministic/stochastic method for dose computations in a filtered BNCT beam. Larsson, B [Editor], Crawford, J [Editor], Weinreich, R [Editor] International Congress Series; Advances in Neutron capture therapy, Vol 1 Medicine and physics 248-252